indometacin

Indometacin is a potent non-steroidal anti-inflammatory drug (NSAID) belonging to the indole acetic acid derivative class. It functions as a non-selective inhibitor of the cyclooxygenase enzymes COX-1 and COX-2, which are responsible for the synthesis of prostaglandins from arachidonic acid. By reducing prostaglandin levels, indometacin effectively mitigates pain, fever, and inflammation. The specific product **Tuodu** (also marketed under the **Qingying** trademark) is a rectal suppository formulation manufactured by **Guangdong Xinxing Fenghua Pharmaceutical**. It is widely utilized in clinical practice for the management of inflammatory conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis, as well as for the acute treatment of gouty arthritis and as an antipyretic for high fever.

Brand names

TuoduQingying妥度清营

Other names

Xinxing Tuodu Qingying ShuanIndometacin Suppositories吲哚美辛栓消炎痛栓