Drug intelligence / Profile preview

infanrix-ipv+hib + prevenar

Development stage
Unknown
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

A combination of two separate vaccines that are commonly administered together in childhood immunization schedules. **Infanrix-IPV+Hib** is a combined vaccine that protects against five diseases: diphtheria, tetanus, pertussis (whooping cough), poliomyelitis (polio), and Haemophilus influenzae type b (Hib) disease. It contains: - Diphtheria toxoid: not less than 30 International Units (IU) - Tetanus toxoid: not less than 40 International Units (IU) - Pertussis antigens: - Pertussis toxoid (PT): 25 micrograms - Filamentous haemagglutinin (FHA): 25 micrograms - Pertactin (PRN): 8 micrograms - Poliovirus (inactivated): - Type 1 (Mahoney strain): 40 D-antigen units - Type 2 (MEF-1 strain): 8 D-antigen units - Type 3 (Saukett strain): 32 D-antigen units - Haemophilus influenzae type b polysaccharide (PRP): 10 micrograms conjugated to tetanus toxoid as carrier protein (approximately 25 micrograms) The vaccine is manufactured by GlaxoSmithKline (GSK). **Prevenar (Pneumococcal Conjugate Vaccine)** is a pneumococcal conjugate vaccine that protects against Streptococcus pneumoniae infections. The search results indicate it contains 0.125 milligrams of aluminum as an adjuvant. These vaccines are often administered together as part of childhood immunization schedules, though as separate injections at different sites.

Brand names
Infanrix-IPV+Hib + Prevenar
02

Targets

CPS14 (Streptococcus pneumoniae capsular polysaccharide serotype 14)CPS 18C (Streptococcus pneumoniae capsular polysaccharide serotype 18C)CPS19F (Streptococcus pneumoniae capsular polysaccharide serotype 19F)CPS23F (Streptococcus pneumoniae capsular polysaccharide serotype 23F)CPS4 (Streptococcus pneumoniae capsular polysaccharide serotype 4)6B CPS (Streptococcus pneumoniae serotype 6B capsular polysaccharide)Streptococcus pneumoniae capsular polysaccharide serotype 9V (PnPS 9V)

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