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The Influenza Split Vaccine developed by Zhejiang Tianyuan Biopharmaceuticals is an inactivated, split-virion vaccine indicated for the prevention of influenza. It is produced by treating inactivated influenza viruses with detergents to disrupt the viral envelope, resulting in a 'split' vaccine that contains purified surface antigens, primarily hemagglutinin (HA) and neuraminidase (NA). This modality is designed to induce protective antibody responses while maintaining a favorable safety profile compared to whole-virus vaccines. The product is approved in China and available in 0.25ml and 0.5ml formulations, targeting both pediatric and adult populations.
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