influenza vaccine, trivalent

**Influenza vaccine, trivalent** is a combination vaccine designed to provide active immunization against three strains of influenza viruses: one influenza A(H1N1), one influenza A(H3N2), and one influenza B/Victoria lineage virus[1][3]. It is available as inactivated (IIV3), recombinant (RIV3), and live attenuated (LAIV3) formulations[3]. The mechanism of action is induction of protective immune responses (primarily neutralizing antibodies) against the hemagglutinin antigen proteins of the included viral subtypes, preventing symptomatic infection and transmission. Vaccines are updated annually based on global surveillance data. The vaccine is approved for active immunization across all ages (6 months and older), with specific formulations tailored for different age groups and populations (e.g., high-dose, adjuvanted, intranasal)[3][1]. Primary indication is the prevention of seasonal influenza disease.

Brand names

Fluzone TrivalentFluarix TrivalentFlulaval TrivalentFluMist TrivalentFluBlok TrivalentFluad TrivalentAfluria TrivalentFlucelvax TrivalentFluzone High-Dose Trivalent

Other names

trivalent influenza vaccineseasonal flu vaccine trivalentTIV