influenza vaccine + MF59C.1

A combination vaccine comprising **inactivated influenza virus surface antigens** (hemagglutinin and neuraminidase) from selected circulating strains, **adjuvanted with MF59C.1**, an oil-in-water emulsion-based adjuvant containing squalene. It is designed primarily to enhance the immune response, particularly in older adults (≥65 years). MF59C.1 increases and broadens antigen-specific immunity by promoting local inflammation, recruiting immune cells (notably CD11b+ inflammatory cells) to the injection site, and enhancing both humoral (antibody) and cellular immune responses, including improved T follicular helper and germinal center B cell responses. The formulation and included viral strains are updated annually to match circulating influenza subtypes. Its primary indication is the prevention of influenza.

Brand names

Fluad

Other names

influenza vaccine (surface antigen, inactivated, adjuvanted)MF59-adjuvanted influenza vaccineMF-59-adjuvanted influenza vaccineMF 59-adjuvanted influenza vaccine