influenza vaccine surface antigen, inactivated

Influenza vaccine surface antigen, inactivated, is an **inactivated viral vaccine** used for the **prevention of influenza** disease caused by various influenza A and B virus subtypes contained in the vaccine[1][2][4]. It contains surface antigens—**hemagglutinin (HA) and neuraminidase (NA)**—purified from influenza viruses that have been inactivated, often with an adjuvant like MF59 (squalene oil-in-water emulsion) in some formulations. The vaccine stimulates the immune system to produce antibodies against HA and NA, which neutralize and prevent cell entry of the influenza virus, providing active immunization[3][1][4]. It does not contain live viruses and cannot cause influenza[2][3]. Developed according to World Health Organization recommendations, strain composition is updated yearly to match circulating strains[1][2][4]. The main use is **seasonal influenza prophylaxis** in children, adults, and older adults, with specific products indicated for certain age groups[1][2][4].

Brand names

FluadAgrifluFluad Quadrivalent

Other names

inactivated influenza vaccine surface antigeninactivated influenza virus vaccine surface antigeninactivated influenza vaccine