Drug intelligence / Profile preview

Ingelvac CircoFLEX

Development stage
Unknown
Lead developer
Boehringer Ingelheim
Modality
Split/Subunit Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes, Recombinant Protein Vaccines → Recombinant Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Ingelvac CircoFLEX is a veterinary vaccine indicated for the active immunization of pigs against porcine circovirus type 2 (PCV2). It is a single-dose, inactivated subunit vaccine containing the ORF2 protein of PCV2, produced using a baculovirus vector system. The vaccine is formulated as an aqueous suspension with ImpranFLEX, a proprietary polymer adjuvant that enhances immunogenicity without using oil-based components. Upon intramuscular administration, it induces an immune response that reduces viremia, lymphoid depletion, inflammation and colonization of lymphoid tissue associated with PCV2 infection. Onset of immunity occurs within two weeks post-vaccination and lasts at least four months[1][3][4][5]. The product is developed and manufactured by Boehringer Ingelheim Animal Health.

Brand names
Ingelvac CircoFLEX
Other names
Porcine Circovirus Vaccine Type 2PCV2 vaccine (Ingelvac CircoFLEX)
02

Targets

PCV2 Cap (Porcine circovirus type 2 capsid protein)

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