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iNK cells
- Development stage
- Unknown
- Lead developer
- Guangzhou Ruixin Biotechnology
- Modality
- CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies, Lymphokine-Activated Killer Cells → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies, iPSCs → Pluripotent Stem Cells → Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
iNK cells (Guangzhou Ruixin) is an induced pluripotent stem cell (iPSC)-derived natural killer (NK) cell therapy developed by Guangzhou Ruixin Biotechnological Co., LTD. This 'off-the-shelf' cell therapy involves the differentiation of iPSCs into mature, functional NK cells that possess innate anti-tumor capabilities. The therapy is currently being investigated as a maintenance treatment for patients with small cell lung cancer (SCLC) who have completed chemoradiotherapy. By providing a standardized and scalable source of NK cells, this approach aims to eliminate residual micrometastatic disease and prolong remission in SCLC patients.
- Other names
- iPSC-derived NK cellsinduced pluripotent stem cell-derived natural killer cellsINK Cells
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