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INO-3609
- Development stage
- Phase 1
- Lead developer
- Inovio Pharmaceuticals
- Modality
- Prophylactic Vaccines → Vaccines & Immunotherapeutics, DNA Vaccines → Plasmid DNA → DNA Therapeutics → Nucleic Acid Therapeutics
- Administration
- Intradermal (with Electroporation), Injection
01
Overview
INO-3609 is a DNA-based universal influenza vaccine candidate developed by Inovio Pharmaceuticals. It is designed to provide immunization against both the H5N1 and H1N1 subtypes of the Influenza A virus. The product utilizes Inovio's proprietary SynCon technology to generate a multi-subtype DNA plasmid encoding antigens from these viral strains. Administration is performed with electroporation to enhance cellular uptake and immune response. The mechanism of action involves immunostimulation—eliciting an immune response capable of recognizing and neutralizing multiple strains of Influenza A virus[2][1]. Its primary indication was for the prevention of disease caused by pandemic or seasonal Influenza A viruses.
- Other names
- Multi-subtype SynCon vaccine targeting H1N1 and H5N1 influenzaSynCon H5N1 + H1N1 influenza universal vaccineUniversal influenza (H5N1 + H1N1) SynCon vaccineSeasonal flu vaccine (H5N1 + H1N1)
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