inositol + alpha-lactalbumin

A combination of **inositol** (specifically myo-inositol) and **alpha-lactalbumin** is an oral formulation primarily investigated as a dietary supplement for **improving insulin resistance and reproductive/metabolic disturbances in women with polycystic ovary syndrome (PCOS)**, as well as **reducing insulin resistance and excessive fetal growth in gestational diabetes mellitus (GDM)**[1][3][4][5]. - Myo-inositol is a carbocyclic sugar involved in cellular signaling and metabolic regulation, known to improve insulin sensitivity and ovarian function. - Alpha-lactalbumin is a major whey protein in mammalian milk that not only serves as a nutrient but also aids intestinal absorption of myo-inositol, increases its plasma bioavailability, and may exert anti-inflammatory effects by inhibiting cyclooxygenase-2 (COX2) and decreasing IL-6 levels[4][5]. - In clinical studies, the combination was shown to restore ovulation in myo-inositol-resistant PCOS patients and reduce the need for insulin treatment and pre-term birth rates in GDM[1][3][4][5]. - The combination may also modulate gut microbiota, enhancing myo-inositol absorption[4][5].

Other names

myo-inositol + alpha-lactalbumin