Drug intelligence / Profile preview

inositol-stabilized arginine silicate

Development stage
Unknown
Lead developer
Nutrition21
Modality
Small Molecules
Administration
Oral
01

Overview

**Inositol-stabilized arginine silicate** (ASI) is a complex produced by combining arginine, a silicate salt such as potassium silicate, and inositol. This combination solubilizes the silicate, resulting in high bioavailability for both arginine and silicon. ASI dissociates in the stomach, releasing arginine, silicate, and inositol. It is primarily developed as a dietary and sports supplement for enhancing **circulating arginine and nitric oxide (NO)**, which can increase vasodilation, blood flow, and nutrient delivery. Studies show benefits for **cognitive function**, exercise recovery, muscle damage reduction, and support for cardiovascular health and bone formation. Its main mechanisms relate to improved arginine and silicon bioavailability, leading to elevated NO production and upregulation of physiological processes such as vasodilation and improved cognitive outcomes[1][3][4][5][7].

Brand names
Nitrosigine
Other names
arginine silicate inositol complex
02

Targets

NOS3 (eNOS)

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