Drug intelligence / Profile preview

Inst. of Materia Medica MAO-B compound 6m

Development stage
Unknown
Lead developer
Shanghai Institute of Materia Medica
01

Overview

Inst. of Materia Medica MAO-B compound 6m: sourced facts only. name: "Among them, compounds 6c with a 4'-fluorobenzyl ring and 6m bearing a 3',4'-difluorobenzyl ring on the 3-position were the most potent MAO-B inhibitors with IC50 values of 0.35 μM and 0.32 μM, respectively." [PMID:35472505]; target: "Among them, compounds 6c with a 4'-fluorobenzyl ring and 6m bearing a 3',4'-difluorobenzyl ring on the 3-position were the most potent MAO-B inhibitors with IC50 values of 0.35 μM and 0.32 μM, respectively." [PMID:35472505]; developer: "Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China." [PMID:35472505]

02

Targets

MAOB (Monoamine oxidase B)

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