Instat

Instat is a topical hemostatic agent composed of purified bovine dermal collagen, designed for use in surgical procedures to control bleeding when conventional methods like pressure or ligatures are ineffective. Developed by Ethicon, a subsidiary of Johnson & Johnson, Instat provides a mechanical matrix that facilitates the rapid adhesion and aggregation of platelets upon contact with blood. This interaction triggers the intrinsic coagulation cascade, leading to the formation of a stable fibrin clot. The product is biocompatible and fully absorbable, typically being resorbed by the body within 4 to 6 weeks. It is available in various forms, such as sponges and pads, and is widely utilized across surgical specialties including general, vascular, and orthopedic surgery.

Brand names

InstatInstat MCH

Other names

Microfibrillar collagen hemostatBovine collagen hemostatCollagen absorbable hemostat