insulin + glucose + potassium chloride + magnesium sulfate

TGC-Prince of Songkla University-hyperglycemia refers to a specific therapeutic protocol for intraoperative tight glycaemic control (TGC) developed and evaluated by researchers at the Prince of Songkla University. The intervention utilizes a hyperinsulinaemic normoglycaemic clamp technique, which involves the continuous intravenous infusion of insulin (specifically Humulin R) at a fixed rate, supplemented by a separate infusion of a modified glucose-insulin-potassium (GIK) solution. This GIK mixture contains 25% glucose, potassium chloride, and magnesium sulfate, and is titrated to maintain blood glucose levels within a target range of 80-150 mg/dL. The protocol is primarily indicated for patients undergoing cardiac surgery to mitigate the risks of postoperative infection, morbidity, and mortality associated with intraoperative hyperglycemia.

Other names

Tight Glycaemic Controlhyperinsulinaemic normoglycaemic clampmodified glucose-insulin-potassiumGIK