Drug intelligence / Profile preview

insulin aspart-szjj

Development stage
Approved
Lead developer
Tonghua Dongbao
Modality
Fab Fragments → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, scFv Fragments → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, Nanobodies (VHH) → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Administration
Subcutaneous
01

Overview

Merilog (insulin aspart-szjj) is a rapid-acting human insulin analog biosimilar to NovoLog (insulin aspart), approved for improving glycemic control in adults and pediatric patients with diabetes mellitus. It is administered subcutaneously within 5–10 minutes before a meal and is available in both 10 mL multiple-dose vials and 3 mL single-patient-use prefilled pens. The mechanism of action involves increasing peripheral glucose uptake, especially by skeletal muscle and fat, while inhibiting hepatic glucose production. Clinical studies have demonstrated that Merilog provides noninferior glycemic control compared to the reference product with a similar safety profile[1][2][4][6].

Brand names
MerilogMerilog SoloStar
02

Targets

INSR (Insulin receptor)

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