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Insulin-GLP1
- Development stage
- Preclinical
- Lead developer
- Sekkei Bio
- Modality
- Peptides, Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
- Administration
- Oral
01
Overview
Insulin-GLP1 is a preclinical-stage biologic drug candidate being developed by Sekkei Bio for the treatment of diabetes and obesity. Designed as a dual agonist, the molecule targets both the insulin receptor and the glucagon-like peptide-1 (GLP-1) receptor. This fusion or conjugate approach aims to integrate the potent glucose-lowering effects of insulin with the metabolic benefits of GLP-1 receptor activation, such as enhanced insulin secretion, slowed gastric emptying, and weight reduction. The program is currently in the discovery and preclinical development phase, with no clinical data yet available.
- Other names
- insulin + GLP-1Insulin-GLP1 fusion proteinInsulin-GLP-1 fusion proteinInsulin-GLP 1 fusion protein
02
Targets
GLP1R (GLP-1R)INSR (Insulin receptor)
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