intact casein

Intact casein is the primary, naturally structured protein found in milk and dairy products. It is characterized as a 'slow-digesting' protein because it forms a gel or clot (micellar structure) in the acidic environment of the stomach. This property delays gastric emptying and results in a gradual, sustained release of amino acids into the bloodstream over several hours. Due to its slow absorption kinetics, intact casein is investigated for its potential health benefits, including enhancing satiety, reducing overall food intake, and modulating metabolic rate, which may aid in weight management and obesity prevention. It is often contrasted in clinical studies with 'fast-digesting' proteins like whey and hydrolyzed casein to understand how protein absorption speed influences muscle protein synthesis, appetite-regulating hormones (e.g., GLP-1), and substrate oxidation. Research has also explored its role in mitigating age-related muscle loss (sarcopenia) and its effects on metabolic health in individuals with obesity or metabolic syndrome.

Brand names

Miprodan 30Miprodan30Miprodan-30

Other names

caseinmicellar caseincalcium caseinatesodium caseinate