Intensive multifactorial group-Xiang Guang-da-type 2 diabetes mellitus

Intensive multifactorial group-Xiang Guang-da-type 2 diabetes mellitus refers to a specific intensive treatment protocol evaluated in clinical trials led by investigator Xiang Guang-da for patients with newly diagnosed type 2 diabetes mellitus. The regimen involves a comprehensive, multi-drug approach targeting three primary metabolic factors: glycemic control (using insulin and oral hypoglycemic agents to reach an HbA1c target of 5.5-6.0%), lipid management (using statins and fibrates to achieve LDL-C ≤ 1.9 mmol/L), and blood pressure regulation (using ACE inhibitors, ARBs, diuretics, beta-blockers, and calcium-channel blockers to maintain BP between 120/70 and 130/80 mmHg), supplemented by aspirin. The primary objective of this multifactorial intervention is to improve vascular endothelial function and assess the long-term metabolic memory effect on cardiovascular outcomes.

Other names

Intensive multifactorial therapyIntensive multifactorial treatmentIntensive multifactorial group