Drug intelligence / Profile preview

INTERCEPT

Development stage
Unknown
Lead developer
Cerus Corporation
Modality
Small Molecules, Device-based Delivery → Drug Delivery Systems, Peptides
01

Overview

"INTERCEPT" is a non-specific term used to refer to several distinct medical products and systems. These include the **INTERCEPT Blood System**, a pathogen reduction technology designed to inactivate DNA and RNA in bacteria, viruses, and parasites in blood products (whole blood, red blood cells, platelets) using amustaline (S-303) and glutathione (GSH) to reduce transfusion-transmitted infections. It also refers to **Obeticholic Acid (INT-747)**, a small molecule farnesoid X receptor (FXR) agonist used in the treatment of primary biliary cirrhosis. Additionally, "INTERCEPT" is part of the name for **INTERCEPT H3**, a peptide vaccine targeting H3K27M-mutated gliomas, and **INTERCEPT Fibrinogen Complex (IFC)**, a pathogen-reduced cryoprecipitate product used to treat hypofibrinogenemia and hemorrhage.

Brand names
INTERCEPT Blood SystemINTERCEPT H3INTERCEPT Fibrinogen ComplexObeticholic Acid
02

Targets

Pathogen nucleic acid in blood components (Pathogen DNA/RNA)

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