Drug intelligence / Profile preview

INTERCEPT Fibrinogen Complex

Development stage
Phase 4
Lead developer
Cerus Corporation
Modality
Tissue Cells → Other Cell Types → Cell Therapies, Recombinant Proteins and Enzymes
Administration
Intravenous
01

Overview

INTERCEPT Fibrinogen Complex is a pathogen-reduced blood component designed for rapid fibrinogen supplementation in patients experiencing bleeding associated with fibrinogen deficiency. It is produced from plasma using the INTERCEPT Blood System for Cryoprecipitation, which employs amotosalen and UVA illumination to inactivate pathogens by cross-linking nucleic acids. The product contains high concentrations of fibrinogen, factor XIII, von Willebrand factor (vWF), and other key clotting proteins required for effective hemostasis. It is indicated for the treatment and control of bleeding—including massive hemorrhage—associated with fibrinogen deficiency; as second-line therapy for von Willebrand disease when specific products are unavailable; and to control uremic bleeding after other treatments have failed. The product offers a 5-day post-thaw shelf life at room temperature, enabling immediate transfusion readiness and improved inventory management[1][3][4][5][6][7][8].

Brand names
INTERCEPT Fibrinogen ComplexIFC
Other names
Pathogen Reduced Cryoprecipitated Fibrinogen ComplexPRCFC
02

Targets

Coagulation Factor XIIIBB-031 (Von Willebrand factor)

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