Drug intelligence / Profile preview

INTERCEPT Plasma

Development stage
Unknown
Lead developer
Cerus Corporation
Administration
Intravenous
01

Overview

INTERCEPT Plasma for Ebola virus disease is a pathogen-inactivated convalescent plasma therapy developed by Cerus Corporation. It is a medical device/biologic combination product that utilizes the INTERCEPT Blood System technology to treat convalescent plasma collected from Ebola survivors. The system employs a proprietary molecule (amotosalen) activated by ultraviolet (UVA) light to bind and cross-link DNA and RNA in the plasma, thereby inactivating potential pathogens (including Ebola virus, bacteria, and other transfusion-transmitted infections) while preserving therapeutic antibodies. The treated plasma is then transfused into patients with acute Ebola infections to provide passive immunity.

Brand names
INTERCEPT PlasmaINTERCEPT Blood System
Other names
pathogen-inactivated convalescent plasmaEBOV convalescent plasma
02

Targets

Nucleic acids in pathogens and contaminating leukocytes

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