Drug intelligence / Profile preview

interferon alpha D

Development stage
Unknown
Modality
Cytokines & Interferons → Recombinant Proteins and Enzymes
Administration
Subcutaneous, Intramuscularly, Intravenously, Intralesionally
01

Overview

Interferon alpha D is a specific subtype of human interferon alpha proteins, classified as a cytokine within the type I interferon family. Interferons function as naturally occurring proteins with antiviral, immunomodulatory, and antiproliferative properties. Interferon alpha D, like other type I alpha interferons, binds to the type I interferon receptor (IFNAR), activating the JAK-STAT signaling pathway and inducing the expression of numerous interferon-stimulated genes. These genes exert diverse biological activities, including inhibition of viral replication, enhancement of immune cell cytotoxicity, and modulation of cell proliferation and differentiation. The majority of clinical use and data relate to recombinant interferon alpha 2 subtypes (such as alfa-2a and alfa-2b); however, interferon alpha D is recognized as a natural human subtype with similar molecular and functional profiles as other alpha interferons[2][3][5].

Other names
interferon-α DIFN-α D
02

Targets

IFNAR (Immune system modulation via type I interferon receptor)

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