Drug intelligence / Profile preview

interferon beta-1a

Development stage
Approved
Lead developer
Biogen
Modality
Cytokines & Interferons → Recombinant Proteins and Enzymes
Administration
Intramuscular, Subcutaneous
01

Overview

Interferon beta-1a is a recombinant form of human interferon beta, classified as an immunomodulator and cytokine therapy. It is used primarily to treat relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. Interferon beta-1a works by binding to specific cell surface receptors (interferon alpha/beta receptor 1), modulating the immune response, decreasing inflammation in the central nervous system, and reducing nerve damage that leads to MS symptoms. It does not cure MS but can slow disability progression and reduce relapse frequency. The drug is available as intramuscular or subcutaneous injections under several brand names[1][2][3][4][5][6].

Brand names
AvonexAvonex PenAvonex Prefilled SyringeRebifRebif RebidoseCinnovex
Other names
IFN beta 1a
02

Targets

IFNAR2 (Interferon alpha/beta receptor subunit 2)IFNAR (Immune system modulation via type I interferon receptor)

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