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Drug intelligence / Profile preview
interferon-beta-1a + methylprednisolone
- Development stage
- Unknown
- Lead developer
- Biogen
- Modality
- Cytokines & Interferons → Recombinant Proteins and Enzymes, Small Molecules
- Administration
- Intramuscular, Subcutaneous, Intravenous, Oral
01
Overview
Interferon-beta-1a + methylprednisolone is a combination therapy used primarily in the management of relapsing-remitting multiple sclerosis. Interferon-beta-1a is a recombinant form of human interferon that acts as an immunomodulator, reducing inflammation and preventing nerve damage by decreasing the activity of immune cells that attack myelin in the central nervous system. Methylprednisolone is a synthetic corticosteroid with potent anti-inflammatory and immunosuppressive properties, commonly used to manage acute exacerbations or relapses in multiple sclerosis. The combination has been studied as an add-on strategy to reduce relapse rates more effectively than interferon alone[4][5][2].
- Other names
- interferon beta 1aIFN beta 1aMP
02
Targets
GR (Glucocorticoid receptor)IFNAR (Immune system modulation via type I interferon receptor)
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