Drug intelligence / Profile preview

interferon-dengue

Development stage
Preclinical
Lead developer
Canthevac
Modality
Vaccines & Immunotherapeutics
Administration
Intranasal
01

Overview

Interferon-dengue (IFN-Dengue) is a preclinical-stage, interferon-integrated vaccine candidate being developed by Canthevac for the prevention or treatment of dengue fever. Built on Canthevac's proprietary Interferon-integrated Vaccine Platform (IVP), the vaccine incorporates interferon—a protective human cytokine—directly into the vaccine construct targeting the dengue virus. This design is engineered to stimulate both B-cell and T-cell immunity against the virus. To ensure safety, the vaccine undergoes genetic modifications that prevent further replication or infection of other cells, thereby minimizing the risk of vaccine-induced disease while maintaining high immunogenicity.

02

Targets

IFNAR (Immune system modulation via type I interferon receptor)IFNLR1/IL10RB (Interferon lambda receptor 1/Interleukin-10 receptor subunit beta complex)

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