Drug intelligence / Profile preview

Interim Buprenorphine Treatment

Development stage
Unknown
Lead developer
The University of Vermont
Modality
Small Molecules
Administration
Sublingual
01

Overview

Interim Buprenorphine Treatment (IBT) is a technology-assisted pharmacological and behavioral intervention developed by researchers at the University of Vermont to address treatment waitlist delays for individuals with opioid use disorder (OUD). The protocol utilizes buprenorphine (typically in combination with naloxone), a partial mu-opioid receptor agonist, as the primary medication. IBT incorporates computerized medication dispensing devices for at-home use and an Interactive Voice Response (IVR) system for daily monitoring and random call-backs, allowing for reduced in-person clinic visits (e.g., bi-monthly instead of daily). This approach is specifically designed to provide immediate stabilization for patients in rural or underserved areas where traditional comprehensive treatment capacity is limited, bridging the gap until they can enter a standard treatment program.

Other names
Interim Buprenorphine Treatment for Opioid Use DisorderIBT protocol
02

Targets

MOR (Mu opioid receptor)DOR (Opioid Receptor Delta 1)NOP (Nociceptin/orphanin FQ peptide receptor)KOR (Kappa opioid receptor)

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