Drug intelligence / Profile preview

intestinal flora transplantation live capsule

Development stage
Unknown
Lead developer
Shantou Longhu People's Hospital
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Intestinal flora transplantation live capsule is an oral microbial therapy consisting of live commensal bacteria derived from the gastrointestinal tract of healthy donors. Also known as fecal microbiota transplantation (FMT) in capsule form, it is designed to restore microbial diversity and correct dysbiosis in patients with various conditions, including metabolic and inflammatory disorders. In clinical studies conducted by Shantou Longhu People's Hospital, these capsules are being evaluated for their ability to improve glycemic control and reduce systemic inflammatory markers like TNF-α in elderly patients with type 2 diabetes mellitus. The mechanism involves the competitive exclusion of pathogens, production of beneficial metabolites such as short-chain fatty acids, and modulation of the host immune system.

Other names
fecal microbiota transplantation capsuleFMT capsuleintestinal microbiota transplantation capsule

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