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intestinal flora transplantation living capsule
- Development stage
- Preclinical
- Lead developer
- Shantou Longhu People's Hospital
- Modality
- Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Intestinal flora transplantation living capsule is a specific formulation of Fecal Microbiota Transplantation (FMT) delivered orally. It consists of live microorganisms processed from the feces of healthy, screened donors, which are then enclosed in a capsule. The primary goal of this therapy is to restore a healthy and diverse gut microbiome in the recipient to treat diseases associated with gut dysbiosis. The capsules are designed to be taken orally, offering a less invasive alternative to traditional FMT delivery methods like colonoscopy or enema. [9, 15] This form of therapy is under investigation for a wide range of conditions, including recurrent *Clostridioides difficile* infection (rCDI), inflammatory bowel disease (Crohn's disease and ulcerative colitis), obesity, and metabolic disorders such as type 2 diabetes. [4, 6, 9]
- Other names
- fecal microbiota transplant capsuleFMT capsulelyophilized fecal microbiota transplant肠道菌群移植活体胶囊cFMToral fecal microbiota transplant capsule
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