Drug intelligence / Profile preview

Intoleran Quatrase

Development stage
Unknown
Lead developer
Intoleran
Modality
Replacement Enzymes → Therapeutic Enzymes → Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

Intoleran Quatrase is a multi-enzyme digestive supplement designed to aid in the breakdown of fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs). It contains a specific blend of four enzymes: lactase, xylose isomerase, alpha-galactosidase, and invertase. These enzymes target the digestion of lactose, fructose, galactans, and sucrose, respectively. Developed by the company Intoleran, the product is being evaluated in clinical research, including a randomized cross-over controlled feeding trial sponsored by Monash University, to determine its efficacy in maintaining symptom control in adults with irritable bowel syndrome (IBS) who are following a low FODMAP diet. It is formulated as an oral capsule and is certified as Low FODMAP by Monash University.

Brand names
Intoleran QuatraseQuatrase ForteFodmixQuatrase 10,000
Other names
Intoleran Quatrase FODMAP enzyme capsules
02

Targets

KHK-C (Ketohexokinase C)

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