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Drug intelligence / Profile preview
Intragly-IM
- Development stage
- Phase 3
- Lead developer
- Intra Life
- Modality
- Small Molecules
- Administration
- Inhalation
01
Overview
Intragly-IM (indacaterol + glycopyrronium + mometasone furoate) is an inhaled fixed-dose triple combination therapy developed by Intra Life for the maintenance treatment of asthma in adults. It combines three active ingredients with complementary mechanisms of action: indacaterol, an ultra-long-acting beta2-adrenergic receptor agonist (LABA) that promotes bronchodilation by relaxing airway smooth muscle; glycopyrronium, a long-acting muscarinic receptor antagonist (LAMA) that prevents bronchoconstriction by blocking muscarinic M3 receptors; and mometasone furoate, an inhaled corticosteroid (ICS) that exerts potent anti-inflammatory effects via glucocorticoid receptor activation. Delivered as an inhalation powder via capsules, Intragly-IM is designed to improve lung function, reduce symptoms, and prevent exacerbations in patients whose asthma is inadequately controlled by dual-therapy regimens.
- Brand names
- INTRAGLY-IM LIFE CAPSIntragly-IM
- Other names
- glycopyrronium + indacaterol + mometasoneindacaterol + glycopyrronium + mometasoneindacaterol + glycopyrronium + mometasone furoateindacaterol acetate + glycopyrronium + mometasone furoate
02
Targets
ADRB2 (β2)GR (Glucocorticoid receptor)CHRM3 (M3)
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