intranasal saline

Intranasal saline is a sterile solution of sodium chloride in water, utilized as a placebo control in clinical research conducted by Virginia Polytechnic Institute and State University. In the context of studies investigating the neural correlates of memory and potential treatments for Alzheimer's disease, it is administered via the Precision Olfactory Delivery (POD) device. This delivery system targets the olfactory region to facilitate direct nose-to-brain transport, mirroring the administration of active agents like intranasal insulin. As an inert substance, saline allows for the assessment of the delivery device's effects and provides a comparative baseline to isolate the specific cognitive and neurological impacts of the experimental drug being tested.

Other names

saline solutionsodium chloride nasal sprayintranasal sodium chloride