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Drug intelligence / Profile preview
Intravenous Ibuprofen
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
Intravenous Ibuprofen (IVIb) is a pharmaceutical drug used for the management of pain and fever, particularly in postoperative settings and for conditions like traumatic rib fractures. As a non-steroidal anti-inflammatory drug (NSAID), its mechanism of action involves the inhibition of cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, which leads to a reduction in prostaglandin synthesis. This inhibition results in analgesic, antipyretic, and anti-inflammatory effects. Studies have shown IVIb to be effective in reducing postoperative pain, fever, and opioid consumption, with a favorable safety profile.
- Other names
- Ibuprofen Injection
02
Targets
Amyloid fibrilsPGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ALB (Human serum albumin)
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