inulin-type fructans

Inulin-type fructans are a **non-digestible prebiotic fiber mixture** composed mainly of inulin and shorter-chain fructooligosaccharides/oligofructose that is administered orally to modulate the gut microbiota rather than to act through a single receptor target. In the provided human studies, ITF was used as a nutritional intervention in adults with overweight or obesity, including a randomized placebo-controlled trial in obese women receiving 16 g/day for 3 months, where treatment increased **Bifidobacterium** species and *Faecalibacterium prausnitzii*, reduced circulating lipopolysaccharide-associated metabolic endotoxemia, and was associated with modest changes in adiposity and metabolic markers. ITF is better characterized as a **dietary prebiotic/nutraceutical ingredient** than a conventional pharmaceutical asset; it has also been studied in snack-bar formulations with whey protein for appetite control and, in separate nonclinical work, in obesity-associated inflammation models.

Other names

inulin-type fructansITF prebioticsITFinulin/oligofructose 50/50 mixoligofructose-enriched inulininulin and oligofructoseSynergy 1Synergy1Synergy-1