Drug intelligence / Profile preview

INV-7082

Development stage
Preclinical
Lead developer
Ionova Life Science
Modality
Small Molecules
01

Overview

INV-7082 is a preclinical-stage small molecule antagonist of the Prostaglandin E receptor 4 (EP4), developed by Ionova Life Sciences for the treatment of inflammatory pain. The EP4 receptor is a high-affinity G protein-coupled receptor for prostaglandin E2 (PGE2) and is heavily involved in the sensitization of nociceptors and the mediation of inflammatory responses. By selectively blocking EP4 signaling, INV-7082 aims to provide potent analgesic and anti-inflammatory effects while potentially avoiding the gastrointestinal and cardiovascular side effects associated with non-selective cyclooxygenase (COX) inhibitors. The drug is currently undergoing preclinical evaluation to support its transition into clinical trials.

02

Targets

PTGER4 (Prostaglandin E2 receptor EP4 subtype)

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