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Investigational denture adhesive cream is a medical device developed by GSK intended to enhance the retention and stability of full dentures. It is applied topically to the denture base to create a physical and chemical seal between the prosthetic and the oral mucosa. By increasing the adhesive and cohesive forces, the product aims to improve the maximum incisal bite force and overall patient satisfaction, as measured by the Kapur-Olshan (KO) index. Clinical evaluations, such as trial NCT02411201, have compared its performance against established products like Super Poligrip Free and no-adhesive controls.
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