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IO-0001 is an immune stimulating antibody conjugate (ISAC) that was initially developed by Orum Therapeutics. The drug was designed for the treatment of neoplasms (cancers). As an ISAC, it likely functions by combining the targeting specificity of antibodies with immune-stimulating payloads to enhance anti-tumor immune responses. However, specific details about its molecular target or mechanism of action have not been disclosed publicly. The development of IO-0001 has been discontinued and it is no longer in active clinical development[1].
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