Iodohippurate sodium I-123

Iodohippurate sodium I-123 is a radiopharmaceutical diagnostic agent used primarily to evaluate effective renal plasma flow (ERPF) and kidney function. It consists of o-iodohippuric acid labeled with the radioactive isotope iodine-123. After intravenous administration, it is rapidly cleared from the bloodstream by the kidneys and excreted in urine, allowing for dynamic imaging of renal perfusion and function using gamma cameras or SPECT. The mechanism of action involves filtration and tubular secretion by the kidneys; its pharmacokinetics make it suitable for quantitative assessment of renal plasma flow. It is not used therapeutically but as a diagnostic tool in nuclear medicine[1][2][3][7].

Brand names

NephroflowHippuran I 123

Other names

o-iodohippuric acid I-123ortho-iodohippurate sodium I-123