iodoindomethacin

Iodoindomethacin is a synthetic analog of indomethacin, classified as a benzoylindole derivative. It features an iodine atom at the para position of the benzoyl group and retains the indole acetic acid core structure. Iodoindomethacin acts as an inhibitor of prostaglandin G/H synthase 1 (also known as cyclooxygenase 1 or COX‑1), similar to its parent compound indomethacin, and is used primarily in research settings rather than clinical practice. Its mechanism involves binding to and inhibiting COX‑1, thereby reducing prostaglandin synthesis[3][6]. There are no approved therapeutic indications or marketed products containing this compound.

Other names

1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID2-[1-(4-IODOBENZOYL)-5-methoxy–2-methyl–1H-indol–3–yl]acetic acid1-(4-IODOBENZOYL)-5-methoxy–2-methylindole–3-acetic acid[1-(4-Iodobenzoyl)-5-methoxy–2-methylindol–3-y]acetic acid