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IOH-006 is a bispecific antibody drug candidate developed by Immuneoncia Therapeutics. Its mechanism of action is as a CD47 inhibitor, targeting the CD47 protein (Cluster of Differentiation 47). By inhibiting CD47, which acts as a "don't eat me" signal on tumor cells, the drug aims to enhance immune-mediated clearance of cancer cells. As of April 2025, its highest development status is in the Discovery phase and there are no reported active or inactive clinical indications publicly disclosed[1].
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