Drug intelligence / Profile preview

iopamidol

Development stage
Approved
Lead developer
Bracco Diagnostics
Modality
Small Molecules
Administration
Intravenous, Intrathecal, Oral, Rectal, Intra-arterial
01

Overview

Iopamidol is a nonionic, water-soluble, low-osmolality iodinated radiographic contrast medium. Developed by **Bracco**, it is widely utilized in diagnostic imaging procedures such as computed tomography (CT), angiography, and urography. The drug works by absorbing X-rays as they pass through the body, thereby enhancing the visibility of blood vessels, organs, and lymphatic structures. It is particularly noted for its improved safety profile and lower risk of contrast-induced nephrotoxicity compared to older ionic, high-osmolality agents. Clinical applications include sentinel lymph node mapping in breast cancer, coronary angiography, and peripheral vascular imaging.

Brand names
IsovueIopamironIopamiroScanluxGastromiro
Other names
iopamidolumN,N'-bis(1,3-dihydroxypropan-2-yl)-5-[(2S)-2-hydroxypropanamido]-2,4,6-triiodoisophthalamide

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