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Iophendylate is a highly lipophilic iodine-containing agent used as a contrast medium, primarily for brain and spinal cord visualization. It was commonly used in myelography studies but has been largely replaced by water-soluble agents due to its potential to cause arachnoiditis and other complications. The mechanism of action involves being opaque to X-rays, allowing for visualization of internal structures. It was developed by Alcon Laboratories, Inc.
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