iothalamate

Iothalamate is an iodinated radiopaque contrast medium and diagnostic agent used primarily for medical imaging and the assessment of renal function. As a marker for glomerular filtration rate (GFR), it is considered a reference standard because it is filtered by the glomeruli without significant tubular secretion or reabsorption. It is available in non-radioactive formulations (e.g., Conray) for various diagnostic procedures, including excretory urography, angiography, and CT scan enhancement of the brain and abdominal organs. Additionally, radioisotopic versions such as iothalamate sodium I-125 (Glofil-125) are utilized for precise GFR measurement, while Iotrex (sodium iothalamate I-125) was developed as a liquid radiation source for the GliaSite radiation therapy system to treat brain cancer via internal brachytherapy.

Brand names

ConrayConray 43Conray43Conray-43Cysto-Conray IIGlofil-125Glofil125Glofil 125Iotrex

Other names

iothalamic acidiothalamate meglumineiothalamate sodiumsodium iothalamatemeglumine iothalamateradioisotopic iothalamate