Drug intelligence / Profile preview

ioxaglic acid

Development stage
Unknown
Lead developer
Guerbet
Modality
Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous, Intra-arterial, Intrauterine
01

Overview

Ioxaglic acid is a tri-iodinated benzoate compound used as a low-osmolality iodinated contrast agent for X-ray imaging procedures such as angiography, phlebography, urography, computed tomography (CT), and hysterosalpingography. It is typically administered in the form of its salts—ioxaglate meglumine and ioxaglate sodium. The drug works by absorbing X-rays due to its iodine content, making blood vessels and organs more visible on radiographic images. Ioxaglic acid has lower osmolality than older contrast agents, resulting in fewer side effects. It is rapidly distributed after intravenous administration and excreted unchanged via the kidneys. The primary developer and manufacturer was Guerbet; marketing in the US has been discontinued but it may still be available in some European countries[1][2][3][4][5].

Brand names
Hexabrix
Other names
ioxaglateioxaglate meglumineioxaglate sodium
02

Targets

F2 (Thrombin)

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