Drug intelligence / Profile preview

ipecacuanha extract

Development stage
Unknown
Lead developer
Inga Pharmaceuticals
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Ipecacuanha extract is a botanical extract obtained from the dried roots and rhizomes of *Carapichea ipecacuanha* (also known as *Cephaelis ipecacuanha*). The extract contains bioactive alkaloids, most notably emetine and cephaeline, which exert therapeutic effects. It is primarily utilized as an emetic to induce vomiting in the emergency management of certain types of poisoning, functioning via local irritation of the gastric mucosa and central stimulation of the chemoreceptor trigger zone in the medulla. Additionally, it is used in sub-emetic doses as an expectorant in cough preparations to facilitate the clearance of bronchial secretions. Inga Pharmaceuticals serves as a bulk manufacturer and supplier of this pharmaceutical-grade extract.

Other names
ipecac extractCephaelis ipecacuanha extractCarapichea ipecacuanha extractRadix Ipecacuanhae
02

Targets

CYP3A4 (Cytochrome P450 3A4)

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