Drug intelligence / Profile preview

ipomoea cairica ethyl acetate extract

Development stage
Preclinical
Lead developer
Central University of Technology
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Ipomoea cairica ethyl acetate extract is a botanical extract derived from the stems and leaves of *Ipomoea cairica* (commonly known as mile-a-minute vine or morning glory). The extract contains various bioactive phytochemicals, including alkaloids, saponins, phenols, flavonoids, phytosterols, tannins, triterpenoids, and anthraquinones. It has been investigated for its significant antioxidant and antiproliferative activities, particularly against breast cancer cell lines such as MCF-7, MDA-MB-231, and the triple-negative breast cancer line 4T1. Additionally, the ethyl acetate fraction of *Ipomoea cairica* has demonstrated potential antidiabetic activity through the inhibition of alpha-glucosidase and alpha-amylase enzymes.

Other names
Ipomoea cairica ethyl acetate extractIpomoea cairica ethyl acetate fraction
02

Targets

AMY (Pancreatic alpha-amylase)PTPN1 (Protein tyrosine phosphatase 1B)Sucrase-Isomaltase

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