Drug intelligence / Profile preview

Ipomoea cairica methanol extract

Development stage
Unknown
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Ipomoea cairica methanol extract is a plant-derived research compound obtained from the leaves, flowers, or roots of *Ipomoea cairica* (L.) Sweet, a member of the Convolvulaceae family commonly known as the railway creeper. The extract contains a complex mixture of phytochemicals, including flavonoid glycosides, sulphated flavonoids, arctigenin, matairesinol, trans-2,3-dibenzylbutyrolactone, vanillic acid, β-sitosterol, stigmasterol, and various fatty acids. Preclinical studies have investigated the extract for its potential antioxidant, antiproliferative, antimicrobial, larvicidal, hepatoprotective, and antidiabetic properties. It has demonstrated in vitro cytotoxicity against several cancer cell lines, including breast cancer (MCF-7, MDA-MB-231, 4T1), prostate cancer (LNCaP), and lung cancer (A549), as well as inhibitory activity against α-glucosidase and α-amylase. The extract is primarily used as a research tool and has not advanced to clinical development.

Other names
Ipomoea cairica methanolic extract
02

Targets

AMY (Pancreatic alpha-amylase)PTPN1 (Protein tyrosine phosphatase 1B)Sucrase-Isomaltase

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