Drug intelligence / Profile preview

IR208

Development stage
Phase 3
Lead developer
Immune Response BioPharma
Modality
Peptides, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

IR208 (also known as IR-208 or AI 208) is a first-in-class therapeutic T-cell receptor (TCR) peptide vaccine developed for the treatment of multiple sclerosis, particularly secondary progressive multiple sclerosis. It acts as an immunostimulant by targeting specific T-cell populations to modulate immune responses implicated in the pathogenesis of multiple sclerosis. The drug has received orphan drug designation for this indication and is being developed by Immune Response BioPharma and Orchestra Therapeutics. The product is also referred to under the brand name NeuroVax[4][1][2].

Brand names
NeuroVax
Other names
V beta 17Multiple sclerosis vaccine - Immune Response BioPharma
02

Targets

TRBV (T-cell receptor beta variable chain family)

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