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iricoxib
- Development stage
- Unknown
- Lead developer
- Merck
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Iricoxib is a nonsteroidal anti-inflammatory drug (NSAID) of the coxib class, structurally and pharmacologically related to etoricoxib. It acts as a selective cyclooxygenase-2 (COX-2) inhibitor, reducing the synthesis of prostaglandins involved in pain and inflammation. Like other COX-2 inhibitors, it is designed to provide anti-inflammatory and analgesic effects with reduced gastrointestinal side effects compared to traditional NSAIDs that inhibit both COX-1 and COX-2. Iricoxib is primarily indicated for the management of pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gouty arthritis, and other musculoskeletal disorders.
- Brand names
- iricoxib
- Other names
- iricoxib
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)
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