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iron + doxorubicin
- Development stage
- Preclinical
- Modality
- Nanoparticles → Drug Delivery Systems, Small Molecules
- Administration
- Intravesical
01
Overview
Iron + doxorubicin refers here to an experimental composite antineoplastic formulation in which iron oxide nanoparticles are combined with doxorubicin, specifically reported as Fe3O4 and doxorubicin encapsulated in Spora Lygodii for magnetically guided microrobot-based bladder cancer therapy. The therapeutic concept is that doxorubicin provides the cytotoxic antitumor effect through DNA intercalation and topoisomerase II inhibition, while the iron oxide component enables magnetic responsiveness for active targeting and localized delivery. Based on the provided context, this is not an approved named pharmaceutical product but a research-stage nanoparticle or microrobot drug-delivery formulation investigated for bladder cancer.
- Other names
- Fe/DOX@SLFe3O4 + doxorubicin
02
Targets
TOP2A (DNA topoisomerase II)DNA
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