Drug intelligence / Profile preview

iron + folic acid + cyanocobalamin (Clinique Pasteur)

Development stage
Unknown
Lead developer
Clinique Pasteur
Modality
Small Molecules
Administration
Intravenous, Oral
01

Overview

"iron + vitamin" refers to a combination therapeutic intervention used in Patient Blood Management (PBM) protocols, specifically studied by Clinique Pasteur in Toulouse, France. The regimen consists of intravenous iron (iron injections) administered alongside oral vitamin B12 (cyanocobalamin) and folic acid. This combination is designed to systematically correct preoperative and postoperative iron and nutritional deficiencies in patients undergoing elective cardiac surgery involving extracorporeal circulation. By stimulating erythropoiesis and optimizing red blood cell production, the intervention aims to treat perioperative anemia and significantly reduce the clinical requirement for allogeneic red blood cell transfusions, thereby mitigating transfusion-related risks and improving surgical outcomes.

Other names
iron + vitaminPBMc protocol drug intervention
02

Targets

Vitamin B12-dependent enzymes and transport system1C metabolism (One-carbon metabolism)

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